Postdoctoral Researcher (f,m,d) in Medicinal and Organic Chemistry

Helmholtz-Zentrum für Infektionsforschung GmbH (HZI)
Braunschweig
The department ‘Chemical Biology’, led by Prof. Brönstrup, at the Helmholtz Centre for Infection Research (HZI), is offering positions for

2 Postdoctoral Researchers (f,m,d)

in Medicinal and Organic Chemistry (Synthesis)
The Helmholtz Centre for Infection Research GmbH (HZI) is a member of the Helmholtz Association of German Research Centers, the largest scientific organization in Germany. Scientists at the HZI develop strategies to better combat infectious diseases. Their goal is to develop novel approaches for the prevention, diagnosis and therapy of infectious diseases. To this end, they study bacterial and viral pathogens and their interaction with the immune system and explore new active ingredients.

The strategic aim of the department ‘Chemical Biology’ is to discover and characterize novel anti-infectives through screening, mode of action studies and chemical synthesis.

Responsibilities

The successful candidates will be responsible for the synthetic optimization of novel antibacterial or antiviral compounds. The projects are directed at the design and multistep synthesis of compounds (small molecules or multifunctional drug conjugates, including natural products) at the hit-to-lead and lead-to-candidate stages with pronounced antibacterial or antiviral activity. The bioprofiling will be partly done on site, so the incumbent will get profound exposure to chemistry as well as infection biology.

Requirements

Candidates should have a completed Ph.D. degree in synthetic organic chemistry, as proven by high quality scientific publications. Candidates should be motivated and be able to design and conduct multistep synthesis. Profound knowledge in organic chemistry, purification and analytical tools such as HPLC/MS and NMR spectroscopy are mandatory. Interested applicants should have an overview knowledge on drug research. Experience in natural product chemistry and biological compound profiling is considered as an advantage. The ability to work in a multidisciplinary and international team is mandatory.

We offer

• challenging and varied tasks in a dynamic and international research environment
• most modern workplace equipment
• additional services of the public service
• extensive further training opportunities
• flexible working hours and workplace design
• Support for a better balance between work and private life through our family office
• a workplace at the Science Campus Brunswick-South

Severely handicapped persons with equivalent professional qualifications are given preference. In order to protect your rights, we ask you to provide us with a clearly recognizable reference to the existence of a degree of severe disability in your cover letter or resume. The HZI strives for professional equality between women and men. The position is suitable for part-time work.

Starting date:

As soon as possible. The contract will initially run 2 years.

Salary:

E13 TVöD Bund

Working hours:

39 hours per week

Place of work:

Braunschweig

Probation period:

6 months

Closing date:

28.05.2023
When sending us your application documents, please confirm that you have read our privacy policy and that you agree to the processing of your personal data. Please use the text module in our

for this purpose.
Without these declarations we cannot consider or process your application and will immediately delete any application documents already received after the application deadline.

For further information, please contact
Prof. Mark Brönstrup

, phone 0531 6181-3400, e-mail:
Please send your complete application, quoting the
HZI reference number 64/2023
, to the Helmholtz Centre for Infection Research GmbH, Human Resources Department, Inhoffenstr. 7, 38124 Braunschweig, Germany or by e-mail to
. If you send your application in electronic form, please provide
a summary in one single (1) pdf document.
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